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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク RAR-related orphan receptor alpha ： ウィキペディア英語版 RAR-related orphan receptor alpha RAR-related orphan receptor alpha (RORα), also known as NR1F1 (nuclear receptor subfamily 1, group F, member 1) is a nuclear receptor that in humans is encoded by the ''RORA'' gene. RORα participates in the transcriptional regulation of some genes involved in circadian rhythm.〔 == Discovery == The first three human isoforms of RORα were initially cloned and characterized as nuclear receptors in 1994 by Giguère and colleagues, when their structure and function were first studied. In the early 2000s, various studies demonstrated that RORα displays rhythmic patterns of expression in a circadian cycle in the liver, kidney, retina, and lung.〔 Of interest, it was around this time that RORα abundance was found to be circadian in the mammalian suprachiasmatic nucleus.〔 RORα is necessary for normal circadian rhythms in mice,〔 demonstrating its importance in chronobiology. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「RAR-related orphan receptor alpha」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.